RT Journal Article SR Electronic T1 Additional Surgical Resection After Endoscopic Resection for Patients With High-risk T1 Colorectal Cancer JF In Vivo JO In Vivo FD International Institute of Anticancer Research SP 1243 OP 1248 DO 10.21873/invivo.11596 VO 33 IS 4 A1 KENTA IGUCHI A1 HIROYUKI MUSHIAKE A1 TORU AOYAMA A1 HIROKAZU SUWA A1 NORIO YUKAWA A1 MITSUYOSHI OTA A1 YASUSHI RINO A1 CHIKARA KUNISAKI A1 ITARU ENDO A1 MUNETAKA MASUDA YR 2019 UL http://iv.iiarjournals.org/content/33/4/1243.abstract AB Background/Aim: The purpose of this study was to reveal the safety and efficacy of additional surgical resection (ASR) for high-risk T1 colorectal cancer (CRC) after endoscopic resection (ER). Patients and Methods: We retrospectively analyzed 191 patients with high-risk T1 CRC after ER. Results: The ASR was performed in 176 (92.1%) patients and 15 (7.9%) rejected ASR. All patients that underwent ASR experienced R0 resection; laparoscopic surgery was performed in 159 (90.3%) patients. Clavien–Dindo complications ≥grade II occurred in 33 patients (18.8%). Anastomotic leakage (8.5%) and ileus (5.7%) were the most frequent complications. The anus function was preserved in all patients. Metastatic lymph node was detected in 21 (11.9%) patients. There were no deaths or relapses in patients with ASR. One patient without ASR (6.7%) had a lymph node recurrence. Conclusion: ASR was safe and effective and is recommended for high-risk T1 CRC patients after ER. A satisfactory long-term outcome can be achieved.