PT - JOURNAL ARTICLE AU - PHAM CAM PHUONG AU - LE VIET NAM AU - STEVEN E. SCHILD AU - DIRK RADES AU - MAI TRONG KHOA TI - A Survival Score Based on Symptoms and Performance Status for Patients with High-grade Gliomas Receiving Radiochemotherapy DP - 2017 Jul 01 TA - In Vivo PG - 689--693 VI - 31 IP - 4 4099 - http://iv.iiarjournals.org/content/31/4/689.short 4100 - http://iv.iiarjournals.org/content/31/4/689.full SO - In Vivo2017 Jul 01; 31 AB - Aim: To create a simple survival score for patients with high-grade gliomas based on clinical symptoms and performance status. Patients and Methods: Thirty-six patients received neurosurgical intervention followed by radiochemotherapy for high-grade gliomas. Six pre-treatment symptoms were included in the score depending on their impairment of quality of life, scoring each between 1 and 3. For each patient, the points from the symptoms were added and another 4 points were added for Karnofsky performance status (KPS) <80%. Based on the survival rates of these scores, two groups were formed: 1-4 (group A) and 5-12 points (group B). Results: The 1-, 2- and 3-year survival rates in group A were 100%, 33% and 24% in group A and 47%, 7% and 0% in group B (p<0.001). In addition, complete tumor resection (p<0.001) and tumor grade III (p<0.001) were associated with improved survival. Conclusion: A simple survival score was developed helping physicians in decision-making for patients with high-grade gliomas.