RT Journal Article SR Electronic T1 Predictive Factors for Prolonged Urination Disorder After Permanent 125I Brachytherapy for Localized Prostate Cancer JF In Vivo JO In Vivo FD International Institute of Anticancer Research SP 755 OP 761 VO 31 IS 4 A1 HIDEHISA MORI A1 TOMOHARU FUKUMORI A1 KEI DAIZUMOTO A1 MEGUMI TSUDA A1 YOSHIHITO KUSUHARA A1 TOMOYA FUKAWA A1 YASUYO YAMAMOTO A1 KUNIHISA YAMAGUCHI A1 MASAYUKI TAKAHASHI A1 AKIKO KUBO A1 TAKASHI KAWANAKA A1 SHUNSUKE FURUTANI A1 HITOSHI IKUSHIMA A1 HIRO-OMI KANAYAMA YR 2017 UL http://iv.iiarjournals.org/content/31/4/755.abstract AB Background: We assessed the change in LUTS after prostate brachytherapy to reveal factors for prolonged urination disorder. Materials and Methods: Four hundred and four patients received prostate brachytherapy at our institution and were followed-up for at least 2 years. We evaluated the correlation of mean IPSS changes and clinical factors. Using multivariate analysis, we also evaluated clinical factors with potential to delay IPSS resolution. Results: In cases with prostate volume more than 30 cm3, radiation dose to 90% of prostate volume (D90) more than 160 Gy, and radiation dose to 30% of the urethral volume (UD30) more than 240 Gy, mean IPSS levels were significantly higher, even 30 months after treatment. On multivariate analysis, baseline IPSS more than 8 points and D90 more than 160 Gy were significant predictors for delayed IPSS resolution. Conclusion: Our data suggest that higher baseline IPSS and higher D90 were predictors for prolonged urination disorder.