TY - JOUR T1 - Predictive Factors for Prolonged Urination Disorder After Permanent <sup>125</sup>I Brachytherapy for Localized Prostate Cancer JF - In Vivo JO - In Vivo SP - 755 LP - 761 VL - 31 IS - 4 AU - HIDEHISA MORI AU - TOMOHARU FUKUMORI AU - KEI DAIZUMOTO AU - MEGUMI TSUDA AU - YOSHIHITO KUSUHARA AU - TOMOYA FUKAWA AU - YASUYO YAMAMOTO AU - KUNIHISA YAMAGUCHI AU - MASAYUKI TAKAHASHI AU - AKIKO KUBO AU - TAKASHI KAWANAKA AU - SHUNSUKE FURUTANI AU - HITOSHI IKUSHIMA AU - HIRO-OMI KANAYAMA Y1 - 2017/07/01 UR - http://iv.iiarjournals.org/content/31/4/755.abstract N2 - Background: We assessed the change in LUTS after prostate brachytherapy to reveal factors for prolonged urination disorder. Materials and Methods: Four hundred and four patients received prostate brachytherapy at our institution and were followed-up for at least 2 years. We evaluated the correlation of mean IPSS changes and clinical factors. Using multivariate analysis, we also evaluated clinical factors with potential to delay IPSS resolution. Results: In cases with prostate volume more than 30 cm3, radiation dose to 90% of prostate volume (D90) more than 160 Gy, and radiation dose to 30% of the urethral volume (UD30) more than 240 Gy, mean IPSS levels were significantly higher, even 30 months after treatment. On multivariate analysis, baseline IPSS more than 8 points and D90 more than 160 Gy were significant predictors for delayed IPSS resolution. Conclusion: Our data suggest that higher baseline IPSS and higher D90 were predictors for prolonged urination disorder. ER -