PT  - JOURNAL ARTICLE
AU  - NAKAMURA, KENJI
AU  - TOMIOKU, MIFUJI
AU  - NABESHIMA, KAZUHITO
AU  - NOMURA, EIJI
TI  - Clinical Implication of the Width of Subserosal Invasion in T3N0 Gastric Cancer
DP  - 2017 May 01
TA  - In Vivo
PG  - 409--413
VI  - 31
IP  - 3
4099  - http://iv.iiarjournals.org/content/31/3/409.short
4100  - http://iv.iiarjournals.org/content/31/3/409.full
SO  - In Vivo2017 May 01; 31
AB  - Background: The aim of this study was to clarify the impact of the horizontal width of tumor invasion into the subserosal layer on prognosis in patients with T3N0 gastric cancer. Patients and Methods: A total of 72 patients with T3N0 cancer were enrolled. Relapse-free survival of the subgroups classified according to width of subserosal invasion was compared to that of 34 patients with T4aN0 cancer. Results: The group with wide invasion (≥1.5 cm) had a significantly poorer prognosis than those with narrow invasion (<1.5 cm) (p=0.014). Multivariate analysis revealed the width of subserosal invasion to be an independent prognostic factor. There was no significant difference between the T3N0 group with wide invasion and the T4aN0 group in the prognosis and recurrent status. Conclusion: The malignant potential of T3N0 gastric cancer with wide subserosal invasion was found to be similar to that of T4aN0 cancer.