RT Journal Article SR Electronic T1 Bone Regeneration of Hydroxyapatite with Granular Form or Porous Scaffold in Canine Alveolar Sockets JF In Vivo JO In Vivo FD International Institute of Anticancer Research SP 335 OP 341 VO 31 IS 3 A1 SEOK JIN JANG A1 SE EUN KIM A1 TAE SUNG HAN A1 JUN SIK SON A1 SEONG SOO KANG A1 SEOK HWA CHOI YR 2017 UL http://iv.iiarjournals.org/content/31/3/335.abstract AB This study was undertaken to assess bone regeneration using hydroxyapatite (HA). The primary focus was comparison of bone regeneration between granular HA (gHA) forms and porous HA (pHA) scaffold. The extracted canine alveolar sockets were divided with three groups: control, gHA and pHA. Osteogenic effect in the gHA and pHA groups showed bone-specific surface and bone mineral density to be significantly higher than that of the control group (p<0.01). Bone volume fraction, bone mineral density, and amount of connective tissue related to disturbing osseointegration of the gHA group was higher than in the pHA group. Quantity of new bone formation of the pHA group was higher than that of the gHA group. This study demonstrated that gHA and pHA are potentially good bone substitutes for alveolar socket healing. For new bone formation during 8 weeks' post-implantation, HA with porous scaffold was superior to the granular form of HA.