PT  - JOURNAL ARTICLE
AU  - SEOK JIN JANG
AU  - SE EUN KIM
AU  - TAE SUNG HAN
AU  - JUN SIK SON
AU  - SEONG SOO KANG
AU  - SEOK HWA CHOI
TI  - Bone Regeneration of Hydroxyapatite with Granular Form or Porous Scaffold in Canine Alveolar Sockets
DP  - 2017 May 01
TA  - In Vivo
PG  - 335--341
VI  - 31
IP  - 3
4099  - http://iv.iiarjournals.org/content/31/3/335.short
4100  - http://iv.iiarjournals.org/content/31/3/335.full
SO  - In Vivo2017 May 01; 31
AB  - This study was undertaken to assess bone regeneration using hydroxyapatite (HA). The primary focus was comparison of bone regeneration between granular HA (gHA) forms and porous HA (pHA) scaffold. The extracted canine alveolar sockets were divided with three groups: control, gHA and pHA. Osteogenic effect in the gHA and pHA groups showed bone-specific surface and bone mineral density to be significantly higher than that of the control group (p<0.01). Bone volume fraction, bone mineral density, and amount of connective tissue related to disturbing osseointegration of the gHA group was higher than in the pHA group. Quantity of new bone formation of the pHA group was higher than that of the gHA group. This study demonstrated that gHA and pHA are potentially good bone substitutes for alveolar socket healing. For new bone formation during 8 weeks' post-implantation, HA with porous scaffold was superior to the granular form of HA.