TY - JOUR T1 - Bone Regeneration of Hydroxyapatite with Granular Form or Porous Scaffold in Canine Alveolar Sockets JF - In Vivo JO - In Vivo SP - 335 LP - 341 VL - 31 IS - 3 AU - SEOK JIN JANG AU - SE EUN KIM AU - TAE SUNG HAN AU - JUN SIK SON AU - SEONG SOO KANG AU - SEOK HWA CHOI Y1 - 2017/05/01 UR - http://iv.iiarjournals.org/content/31/3/335.abstract N2 - This study was undertaken to assess bone regeneration using hydroxyapatite (HA). The primary focus was comparison of bone regeneration between granular HA (gHA) forms and porous HA (pHA) scaffold. The extracted canine alveolar sockets were divided with three groups: control, gHA and pHA. Osteogenic effect in the gHA and pHA groups showed bone-specific surface and bone mineral density to be significantly higher than that of the control group (p<0.01). Bone volume fraction, bone mineral density, and amount of connective tissue related to disturbing osseointegration of the gHA group was higher than in the pHA group. Quantity of new bone formation of the pHA group was higher than that of the gHA group. This study demonstrated that gHA and pHA are potentially good bone substitutes for alveolar socket healing. For new bone formation during 8 weeks' post-implantation, HA with porous scaffold was superior to the granular form of HA. ER -