RT Journal Article SR Electronic T1 Detection of Local Recurrence with 3-Tesla MRI After Radical Prostatectomy: A Useful Method for Radiation Treatment Planning? JF In Vivo JO In Vivo FD International Institute of Anticancer Research SP 125 OP 131 VO 32 IS 1 A1 DANIEL BUERGY A1 METIN SERTDEMIR A1 ANJA WEIDNER A1 MOHAMED SHELAN A1 FRANK LOHR A1 FREDERIK WENZ A1 STEFAN O. SCHOENBERG A1 ULRIKE I. ATTENBERGER YR 2018 UL http://iv.iiarjournals.org/content/32/1/125.abstract AB Background/Aim: Salvage radiotherapy improves biochemical control in patients with recurrence of prostate cancer after prostatectomy. Radiotherapy target volumes of the prostatic fossa are based on empirical data and differ between different guidelines. Localization of recurrence with multiparametric magnetic resonance imaging (MRI) might be a feasible approach to localize recurrent lesions. Patients and Methods: Twenty-one patients with biochemical recurrence after radical prostatectomy were included (median prostate-specific antigen (PSA) =0.17 ng/ml). Multi-parametric MRI was performed using a 3-T MR system. Results: Lesions were detected in seven patients with a median PSA of 0.86 ng/ml (minimum= 0.31 ng/ml). Patients without detectable recurrence had a median PSA of 0.12 ng/ml. All patients with detectable lesions responded to radiotherapy. Eleven out of 14 patients without detectable recurrence also responded. Plasma flow in suspicious lesions was correlated with PSA level. Conclusion: Detection of recurrence at the prostatic fossa with our approach was possible in a minority of patients with a low PSA level. Clinical relevance of plasma flow in suspicious lesions should be further investigated.