RT Journal Article
SR Electronic
T1 Clinical Impact of Rest Dual–energy Computed Tomography Myocardial Perfusion in Patients with Coronary Artery Disease
JF In Vivo
JO In Vivo
FD International Institute of Anticancer Research
SP 1153
OP 1157
VO 31
IS 6
A1 STEFAN BAUMANN
A1 MARLON RUTSCH
A1 TOBIAS BECHER
A1 PHILIPP KRYEZIU
A1 HOLGER HAUBENREISSER
A1 NILS VOGLER
A1 CELI ANNE SCHOENIKE
A1 MARTIN BORGGREFE
A1 STEFAN O. SCHOENBERG
A1 IBRAHIM AKIN
A1 THOMAS HENZLER
A1 DIRK LOSSNITZER
YR 2017
UL http://iv.iiarjournals.org/content/31/6/1153.abstract
AB Background/Aim: To evaluate the hypothesis that patients with suspected coronary artery disease (CAD) assessed using rest dual-energy computed tomography-derived myocardial perfusion imaging (DECT-P), could have fewer invasive coronary angiographies (ICA), showing non-obstructive CAD. Materials and Methods: Patients who had undergone coronary computed tomography angiography (cCTA), rest DECT-P and ICA were analyzed. Results: We evaluated 51 patients (62.7% males, mean age 51.6±12.8 years). Rest DECT-P identified perfusion defects in three (10.7%) of the 28 patients with cCTA negative for luminal stenosis and in 10 (43.5%) of the 23 patients with cCTA positive for luminal stenosis. In total, 21 patients underwent both cCTA and ICA, of which seven (33.3%) showed obstructive CAD. Rest DECT-P revealed false-negative results in four cases (19.1%) and false-positive results in six cases (28.6%). Conclusion: Adding rest DECT-P to cCTA has no incremental diagnostic value over cCTA alone, to exclude haemodynamically significant CAD. Therefore, a rest-stress-DECT-P protocol or a CT-based FFR calculation might be a promising concept to improve diagnostic accuracy in a real clinical setting.