RT Journal Article
SR Electronic
T1 Lymph Node Size on Computed Tomography Images Is a Predictive Indicator for Lymph Node Metastasis in Patients with Colorectal Neuroendocrine Tumors
JF In Vivo
JO In Vivo
FD International Institute of Anticancer Research
SP 1011
OP 1017
VO 31
IS 5
A1 TANAKA, TOSHIAKI
A1 NOZAWA, HIROAKI
A1 KAWAI, KAZUSHIGE
A1 HATA, KEISUKE
A1 KIYOMATSU, TOMOMICHI
A1 NISHIKAWA, TAKESHI
A1 OTANI, KENSUKE
A1 SASAKI, KAZUHITO
A1 MURONO, KOJI
A1 WATANABE, TOSHIAKI
YR 2017
UL http://iv.iiarjournals.org/content/31/5/1011.abstract
AB Background: Colorectal neuroendocrine tumors (NET) are a rare manifestation of colorectal neoplasia, requiring for radical dissection of the regional lymph nodes along with colorectal resection similar to that required for colorectal cancer. However, thus far, no reports have described the ability of computed tomography (CT) to predict lymph node involvement. In this study, we revealed the prediction rate of lymph node metastasis using contrast-enhanced CT. Patients and Methods: A total of 21 patients with colorectal NET undergoing colorectal resection were recruited from January 2010 to June 2016. We compared the CT findings between samples with or without pathologically proven lymph node metastasis, in each field (pericolic/perirectal and intermediate nodes). Results: Within the pericolic/perirectal field, any lymph node larger than 5 mm in the CT images was a predictive indicator of lymph node metastasis with a sensitivity, specificity, and area under ROC curve (AUC) of 66.7%, 87.5%, and 0.844, respectively. Within the intermediate field, any visible lymph node on the CT was a predictive indicator of lymph node metastasis with a sensitivity, specificity, and AUC of 100%, 76.4%, and 0.890, respectively. In addition, when we observed lymph nodes larger than 3 mm on the CT images, the sensitivity and specificity were 100% and 82.4%, respectively, with an AUC of 0.8971. Conclusion: CT images provide predictive information for lymph node metastasis with a high rate of accuracy.