<?xml version='1.0' encoding='UTF-8'?><xml><records><record><source-app name="HighWire" version="7.x">Drupal-HighWire</source-app><ref-type name="Journal Article">17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">PHUONG, PHAM CAM</style></author><author><style face="normal" font="default" size="100%">HUNG, NGUYEN QUANG</style></author><author><style face="normal" font="default" size="100%">NGOC, TRAN BAO</style></author><author><style face="normal" font="default" size="100%">RADES, DIRK</style></author><author><style face="normal" font="default" size="100%">KHOA, MAI TRONG</style></author></authors><secondary-authors></secondary-authors></contributors><titles><title><style face="normal" font="default" size="100%">Rotating Gamma System Irradiation: A Promising Treatment for Low-grade Brainstem Gliomas</style></title><secondary-title><style face="normal" font="default" size="100%">In Vivo</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2017-09-01 00:00:00</style></date></pub-dates></dates><pages><style  face="normal" font="default" size="100%">957-960</style></pages><volume><style face="normal" font="default" size="100%">31</style></volume><issue><style face="normal" font="default" size="100%">5</style></issue><abstract><style  face="normal" font="default" size="100%">Aim: To evaluate the role of rotating gamma system (RGS) radiosurgery for low-grade brainstem gliomas. Patients and Methods: Thirty-seven patients undergoing RGS radiosurgery at the Bach Mai Hospital Hanoi for low-grade brainstem glioma were included in this prospective interventional study. The median RGS dose was 12 Gy (range=8-16 Gy). Endpoints included response to RGS radiosurgery given as change in glioma size (maximum diameter), survival and adverse events. Follow-up was performed for 36 months. Three dose-groups (&lt;13, 13-14 and &gt;14 Gy) were compared for survival. Results: Mean glioma size decreased from 1.87 cm before RGS irradiation to 1.15 cm at 36 months. Mean survival was 39.5 months. Mean survival after &lt;13, 13-14 and &gt;14 Gy were 22.7, 66.7 and 49 months, respectively (p&lt;0.05). Adverse events, mainly reduced appetite, sleep disturbances, headache and edema, were not associated with RGS dose and were easily managed. Conclusion: RGS radiosurgery led to promising results with acceptable toxicity in patients with low-grade brainstem gliomas.</style></abstract></record></records></xml>