RT Journal Article SR Electronic T1 Cytocompatibility of Direct Laser Interference-patterned Titanium Surfaces for Implants JF In Vivo JO In Vivo FD International Institute of Anticancer Research SP 849 OP 854 VO 31 IS 5 A1 HARTJEN, PHILIP A1 NADA, OLA A1 SILVA, THIAGO GUNDELWEIN A1 PRECHT, CLARISSA A1 HENNINGSEN, ANDERS A1 HOLTHAUS, MARZELLUS GROßE A1 GULOW, NIKOLAI A1 FRIEDRICH, REINHARD E. A1 HANKEN, HENNING A1 HEILAND, MAX A1 ZWAHR, CHRISTOPH A1 SMEETS, RALF A1 JUNG, OLE YR 2017 UL http://iv.iiarjournals.org/content/31/5/849.abstract AB In an effort to generate titanium surfaces for implants with improved osseointegration, we used direct laser interference patterning (DLIP) to modify the surface of pure titanium grade 4 of four different structures. We assessed in vitro cytoxicity and cell attachment, as well as the viability and proliferation of cells cultured directly on the surfaces. Attachment of the cells to the modified surfaces was comparably good compared to that of cells on grit-blasted and acid-etched reference titanium surfaces. In concordance with this, viability and proliferation of the cells directly cultured on the specimens were similar on all the titanium surfaces, regardless of the laser modification, indicating good cytocompatibility.