TY - JOUR T1 - Cytocompatibility of Direct Laser Interference-patterned Titanium Surfaces for Implants JF - In Vivo JO - In Vivo SP - 849 LP - 854 VL - 31 IS - 5 AU - PHILIP HARTJEN AU - OLA NADA AU - THIAGO GUNDELWEIN SILVA AU - CLARISSA PRECHT AU - ANDERS HENNINGSEN AU - MARZELLUS GROßE HOLTHAUS AU - NIKOLAI GULOW AU - REINHARD E. FRIEDRICH AU - HENNING HANKEN AU - MAX HEILAND AU - CHRISTOPH ZWAHR AU - RALF SMEETS AU - OLE JUNG Y1 - 2017/09/01 UR - http://iv.iiarjournals.org/content/31/5/849.abstract N2 - In an effort to generate titanium surfaces for implants with improved osseointegration, we used direct laser interference patterning (DLIP) to modify the surface of pure titanium grade 4 of four different structures. We assessed in vitro cytoxicity and cell attachment, as well as the viability and proliferation of cells cultured directly on the surfaces. Attachment of the cells to the modified surfaces was comparably good compared to that of cells on grit-blasted and acid-etched reference titanium surfaces. In concordance with this, viability and proliferation of the cells directly cultured on the specimens were similar on all the titanium surfaces, regardless of the laser modification, indicating good cytocompatibility. ER -