PT - JOURNAL ARTICLE AU - HARTJEN, PHILIP AU - NADA, OLA AU - SILVA, THIAGO GUNDELWEIN AU - PRECHT, CLARISSA AU - HENNINGSEN, ANDERS AU - HOLTHAUS, MARZELLUS GROßE AU - GULOW, NIKOLAI AU - FRIEDRICH, REINHARD E. AU - HANKEN, HENNING AU - HEILAND, MAX AU - ZWAHR, CHRISTOPH AU - SMEETS, RALF AU - JUNG, OLE TI - Cytocompatibility of Direct Laser Interference-patterned Titanium Surfaces for Implants DP - 2017 Sep 01 TA - In Vivo PG - 849--854 VI - 31 IP - 5 4099 - http://iv.iiarjournals.org/content/31/5/849.short 4100 - http://iv.iiarjournals.org/content/31/5/849.full SO - In Vivo2017 Sep 01; 31 AB - In an effort to generate titanium surfaces for implants with improved osseointegration, we used direct laser interference patterning (DLIP) to modify the surface of pure titanium grade 4 of four different structures. We assessed in vitro cytoxicity and cell attachment, as well as the viability and proliferation of cells cultured directly on the surfaces. Attachment of the cells to the modified surfaces was comparably good compared to that of cells on grit-blasted and acid-etched reference titanium surfaces. In concordance with this, viability and proliferation of the cells directly cultured on the specimens were similar on all the titanium surfaces, regardless of the laser modification, indicating good cytocompatibility.