PT  - JOURNAL ARTICLE
AU  - DIRK RADES
AU  - MARKUS DAHLKE
AU  - STEFAN JANSSEN
AU  - NIKLAS GEBAUER
AU  - TOBIAS BARTSCHT
TI  - Radiation Therapy for Metastatic Spinal Cord Compression in Patients with Hepatocellular Carcinoma
DP  - 2015 Nov 01
TA  - In Vivo
PG  - 749--752
VI  - 29
IP  - 6
4099  - http://iv.iiarjournals.org/content/29/6/749.short
4100  - http://iv.iiarjournals.org/content/29/6/749.full
SO  - In Vivo2015 Nov 01; 29
AB  - Aim: This is the first study to investigate patients with metastatic spinal cord compression (MSCC) from hepatocellular carcinoma (HCC). Patients and Methods: Eight patients were analyzed with regard to survival and motor dysfunction. Results: Out of seven factors (age, affected vertebrae, ambulatory status, bone lesions, other distant metastases, time developing motor dysfunction, performance score) ambulatory status (p=0.005) and distant metastases (p=0.032) had a significant influence on survival. Both factors were used as a predictive tool (points: not ambulatory 0, ambulatory 1, distant metastases 0, no distant metastases 1). Total scores were 0, 1 or 2 points. Three-month survival rates were 0%, 67% and 100%, six-month survival rates 0%, 0% and 100%. Progression of motor dysfunction was prevented in 63% of patients; time developing motor deficits showed a trend (p=0.08). Conclusion: Many patients with MSCC from HCC have a short survival, which can be predicted with a new tool. Radiation therapy can stop progression of motor dysfunction.