TY - JOUR T1 - Radiation Therapy for Metastatic Spinal Cord Compression in Patients with Hepatocellular Carcinoma JF - In Vivo JO - In Vivo SP - 749 LP - 752 VL - 29 IS - 6 AU - DIRK RADES AU - MARKUS DAHLKE AU - STEFAN JANSSEN AU - NIKLAS GEBAUER AU - TOBIAS BARTSCHT Y1 - 2015/11/01 UR - http://iv.iiarjournals.org/content/29/6/749.abstract N2 - Aim: This is the first study to investigate patients with metastatic spinal cord compression (MSCC) from hepatocellular carcinoma (HCC). Patients and Methods: Eight patients were analyzed with regard to survival and motor dysfunction. Results: Out of seven factors (age, affected vertebrae, ambulatory status, bone lesions, other distant metastases, time developing motor dysfunction, performance score) ambulatory status (p=0.005) and distant metastases (p=0.032) had a significant influence on survival. Both factors were used as a predictive tool (points: not ambulatory 0, ambulatory 1, distant metastases 0, no distant metastases 1). Total scores were 0, 1 or 2 points. Three-month survival rates were 0%, 67% and 100%, six-month survival rates 0%, 0% and 100%. Progression of motor dysfunction was prevented in 63% of patients; time developing motor deficits showed a trend (p=0.08). Conclusion: Many patients with MSCC from HCC have a short survival, which can be predicted with a new tool. Radiation therapy can stop progression of motor dysfunction. ER -