RT Journal Article
SR Electronic
T1 Predicting Survival After Irradiation for Brain Metastases from Head and Neck Cancer
JF In Vivo
JO In Vivo
FD International Institute of Anticancer Research
SP 525
OP 528
VO 29
IS 5
A1 RADES, DIRK
A1 DZIGGEL, LIESA
A1 HAKIM, SAMER G.
A1 RUDAT, VOLKER
A1 JANSSEN, STEFAN
A1 TRANG, NGO THUY
A1 KHOA, MAI TRONG
A1 BARTSCHT, TOBIAS
YR 2015
UL http://iv.iiarjournals.org/content/29/5/525.abstract
AB Aim: Patients with cerebral metastases from head and neck cancer are not common. This study aimed to create an instrument for estimating survival in this particular group of patients. Patients and Methods: Survival was significantly influenced by Eastern Cooperative Oncology Group (ECOG) performance score, number of cerebral lesions and extracranial metastatic disease. These characteristics were included in our score. Results: Scoring was based on 6-month survival data: ECOG 0-1=1 point, ECOG 2-3=0 points, 1-3 cerebral lesions=1 point, ≥4 cerebral lesions=0 points, lack of extracranial metastases=1 point, and presence of extracranial metastases=0 points. Addition of these points for each patient resulted in 0-3 points. Three groups were built comprising 0-1, 2 and 3 points. Six-month survival rates for these groups were 0%, 50% and 100%, respectively. Conclusion: This new instrument guides physicians in choosing optimal irradiation programs for patients with cerebral metastases from head-and-neck cancer.