RT Journal Article
SR Electronic
T1 Regenerative Medicine for the Treatment of Teno-desmic Injuries of the Equine. A Series of 150 Horses Treated with Platelet-derived Growth Factors
JF In Vivo
JO In Vivo
FD International Institute of Anticancer Research
SP 1119
OP 1123
VO 28
IS 6
A1 MARCO SCALA
A1 SILVIA LENARDUZZI
A1 FRANCESCO SPAGNOLO
A1 MARIA TRAPASSO
A1 CHIARA OTTONELLO
A1 ANITA MURAGLIA
A1 ANNALISA BARLA
A1 PAOLO STRADA
YR 2014
UL http://iv.iiarjournals.org/content/28/6/1119.abstract
AB Background/Aim: The aim of the present study was to evaluate the safety and the clinical outcome of platelet-rich plasma for the treatment of teno-desmic injures in competition horses. Patients and Methods: From January 2009 to December 2011, 150 sport horses suffering from teno-desmic injuries were treated with no-gelled platelet-concentrate. Results: No horse showed any major adverse reaction as a result of the procedure. Full healing was obtained for 81% of the horses. Twelve percent had clinical improvement and only 7% a failure. Eight percent of cases of relapse were observed. No statistically significant correlation existed between clinical outcome and the area of the lesion. A statistically significant correlation existed between the clinical outcome and the age of the horse. Conclusion: Treatment with platelet-derived growth factors leads to the formation of a tendon with normal morphology and functionality, which translate in the resumption of the agonistic activity for the horses we treated.