<?xml version='1.0' encoding='UTF-8'?><xml><records><record><source-app name="HighWire" version="7.x">Drupal-HighWire</source-app><ref-type name="Journal Article">17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">BOONLONG, NUTTANICHA</style></author><author><style face="normal" font="default" size="100%">SALANG, LINGLING</style></author><author><style face="normal" font="default" size="100%">PROUNGVITAYA, SIRIPORN</style></author><author><style face="normal" font="default" size="100%">MARAMING, PORNSUDA</style></author><author><style face="normal" font="default" size="100%">DADUANG, JUREERUT</style></author><author><style face="normal" font="default" size="100%">PONGSRITASANA, THANIDA</style></author><author><style face="normal" font="default" size="100%">SUKKASAME, SINEENART</style></author><author><style face="normal" font="default" size="100%">HAOHAN, SONGPOL</style></author></authors><secondary-authors></secondary-authors></contributors><titles><title><style face="normal" font="default" size="100%">The Asn680Ser Variant Negatively Impacted the Ovarian Response to Controlled Ovarian Stimulation in Thai Female Infertility</style></title><secondary-title><style face="normal" font="default" size="100%">In Vivo</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2026</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2026-05-01 00:00:00</style></date></pub-dates></dates><pages><style  face="normal" font="default" size="100%">1497-1508</style></pages><doi><style  face="normal" font="default" size="100%">10.21873/invivo.14300</style></doi><volume><style face="normal" font="default" size="100%">40</style></volume><issue><style face="normal" font="default" size="100%">3</style></issue><abstract><style  face="normal" font="default" size="100%">Background/Aim: The aim of this study was to evaluate the associations between three follicle-stimulating hormone receptor (FSHR) and FSH β subunit promoter gene polymorphisms, including Asn680Ser, −29G&gt;A, and −211G&gt;T with ovarian response, oocyte maturation, and embryo quality in Thai infertile women.Materials and Methods: A total of 78 infertile Thai women undergoing in vitro fertilization or intracytoplasmic sperm injection were recruited. The polymorphisms were analyzed using polymerase chain reaction - restriction fragments length polymorphism.Results: The Asn680Ser variant was significantly associated with ovarian response. The Asn/Asn genotype was more frequent in hyper-responders (66.7%), while the Asn/Ser genotype predominated among poor responders (71.4%, p=0.038). S-carriers combining Asn/Ser and Ser/Ser genotypes were overrepresented in the poor response group (78.6%, p=0.029). Logistic regression analysis revealed the association between Asn/Ser and S-carriers with poor response [crude odds ratio (OR)= 6.33, 95% confidence interval (CI)=1.56-25.66 and 5.36, 95% CI=1.36-21.10, respectively]. The associations remained after age adjustment (adjusted OR=7.71 95% CI=1.73-34.45 and 6.78, 95% CI=1.57-29.29, respectively). In contrast, −29G&gt;A and −211G&gt;T polymorphisms were not associated with ovarian response. There were not any associations between the three polymorphisms and oocytes maturation and embryo quality.Conclusion: This study is the first to report the association between Asn680Ser FSHR gene polymorphism and the risk of poor response among Thai women.</style></abstract></record></records></xml>