@article {RABIAU203, author = {NADEGE RABIAU and PIERRE DECHELOTTE and LAURENT GUY and SAMIR SATIH and REMY BOSVIEL and LUC FONTANA and JEAN-LOUIS KEMENY and JEAN-PAUL BOITEUX and YVES-JEAN BIGNON and DOMINIQUE BERNARD-GALLON}, title = {Immunohistochemical Staining of Mucin 1 in Prostate Tissues}, volume = {23}, number = {2}, pages = {203--207}, year = {2009}, publisher = {International Institute of Anticancer Research}, abstract = {Prostate cancer is a major public health problem in the world. Molecular studies are necessary for the development of prognostic markers in prostate cancer. There is a great interest in mucin studies in treatment development of human malignancies, including prostate cancer. Nevertheless, their expressions in prostate cancer need further investigation. Materials and Methods: Mucin 1 (MUC1) expression was examined in 100 prostate biopsies and were compared with prostate carcinoma cell lines (DU-145, PC-3, LNCaP) by immunohistochemistry. Results: Biopsies were healthy, tumor, peritumor or presented an intraepithelial neoplasia. Staining of MUC1 was exihibited in PC-3 cells, was higher in DU-145, and was not expressed by LNCaP. Tumor sections presented more positive expression of MUC1 than non-tumor sections. Conclusion: MUC1 expression is correlated with the histological degree of malignancy.}, issn = {0258-851X}, URL = {https://iv.iiarjournals.org/content/23/2/203}, eprint = {https://iv.iiarjournals.org/content/23/2/203.full.pdf}, journal = {In Vivo} }