@article {HUPFELD1, author = {JULIA HUPFELD and THOMAS EFFERTH}, title = {Drug Resistance of Human Immunodeficiency Virus and Overcoming it by Natural Products}, volume = {23}, number = {1}, pages = {1--6}, year = {2009}, publisher = {International Institute of Anticancer Research}, abstract = {Acquired immune deficiency syndrome (AIDS) caused by infection with the human immunodeficiency virus (HIV) represents a major health problem worldwide, especially in developing countries. Combinational anti-HIV therapy has largely improved patients{\textquoteright} lives, but is not widely available in developing countries. Moreover, drug resistance is a main problem during HIV treatment. Therefore, there is a continuous need for new drugs effective against otherwise drug-resistant HIV strains. Chemical compounds from natural sources provide a large variety of potential anti-HIV compounds. The most promising natural products are discussed in this review.}, issn = {0258-851X}, URL = {https://iv.iiarjournals.org/content/23/1/1}, eprint = {https://iv.iiarjournals.org/content/23/1/1.full.pdf}, journal = {In Vivo} }