RT Journal Article
SR Electronic
T1 Postoperative Level of C-Reactive Protein Is a Prognosticator After Esophageal Cancer Surgery With Perioperative Steroid Therapy and Enhanced Recovery After Surgery Care
JF In Vivo
JO In Vivo
FD International Institute of Anticancer Research
SP 587
OP 594
DO 10.21873/invivo.11515
VO 33
IS 2
A1 KAZUKI KANO
A1 TORU AOYAMA
A1 YUKIO MAEZAWA
A1 TSUTOMU HAYASHI
A1 TAKANOBU YAMADA
A1 HIROSHI TAMAGAWA
A1 TSUTOMU SATO
A1 HARUHIKO CHO
A1 TAKAKI YOSHIKAWA
A1 YASUSHI RINO
A1 MUNETAKA MASUDA
A1 TAKASHI OSHIMA
A1 TAKASHI OGATA
YR 2019
UL http://iv.iiarjournals.org/content/33/2/587.abstract
AB Background: This study investigated the impact of postoperative C-reactive protein (CRP) level on survival in patients with esophageal cancer who received perioperative steroid therapy and enhanced recovery after surgery (ERAS) care. Patients and Methods: Overall, 115 patients were retrospectively reviewed. The patients were classified into those with a high CRP level (≥4.0 mg/dl) on postoperative day 4 and those with low CRP level (<4.0 mg/dl). The risk factors for overall survival (OS) and recurrence-free survival (RFS) were identified. Results: The OS and RFS rates at 5 years after surgery were significantly low in patients with high CRP level on postoperative day 4. The multivariate analysis demonstrated that high CRP level on postoperative day 4 was a significant independent risk factor for OS and RFS. Conclusion: The present results suggest that the postoperative CRP level can be a prognosticator in patients with esophageal cancer who have received perioperative steroid therapy and ERAS care.