PT - JOURNAL ARTICLE AU - KAZUKI KANO AU - TORU AOYAMA AU - YUKIO MAEZAWA AU - TSUTOMU HAYASHI AU - TAKANOBU YAMADA AU - HIROSHI TAMAGAWA AU - TSUTOMU SATO AU - HARUHIKO CHO AU - TAKAKI YOSHIKAWA AU - YASUSHI RINO AU - MUNETAKA MASUDA AU - TAKASHI OSHIMA AU - TAKASHI OGATA TI - Postoperative Level of C-Reactive Protein Is a Prognosticator After Esophageal Cancer Surgery With Perioperative Steroid Therapy and Enhanced Recovery After Surgery Care AID - 10.21873/invivo.11515 DP - 2019 Mar 01 TA - In Vivo PG - 587--594 VI - 33 IP - 2 4099 - http://iv.iiarjournals.org/content/33/2/587.short 4100 - http://iv.iiarjournals.org/content/33/2/587.full SO - In Vivo2019 Mar 01; 33 AB - Background: This study investigated the impact of postoperative C-reactive protein (CRP) level on survival in patients with esophageal cancer who received perioperative steroid therapy and enhanced recovery after surgery (ERAS) care. Patients and Methods: Overall, 115 patients were retrospectively reviewed. The patients were classified into those with a high CRP level (≥4.0 mg/dl) on postoperative day 4 and those with low CRP level (<4.0 mg/dl). The risk factors for overall survival (OS) and recurrence-free survival (RFS) were identified. Results: The OS and RFS rates at 5 years after surgery were significantly low in patients with high CRP level on postoperative day 4. The multivariate analysis demonstrated that high CRP level on postoperative day 4 was a significant independent risk factor for OS and RFS. Conclusion: The present results suggest that the postoperative CRP level can be a prognosticator in patients with esophageal cancer who have received perioperative steroid therapy and ERAS care.