PT  - JOURNAL ARTICLE
AU  - ENRICO P. SPUGNINI
AU  - IVAN DOTSINSKY
AU  - NIKOLAY MUDROV
AU  - MASSIMILIANO BUFALINI
AU  - GIOVANNI GIANNINI
AU  - GENNARO CITRO
AU  - FLORINDA FEROCE
AU  - ALFONSO BALDI
TI  - Adjuvant Electrochemotherapy for Incompletely Excised Anal Sac Carcinoma in a Dog
DP  - 2008 Jan 01
TA  - In Vivo
PG  - 47--49
VI  - 22
IP  - 1
4099  - http://iv.iiarjournals.org/content/22/1/47.short
4100  - http://iv.iiarjournals.org/content/22/1/47.full
SO  - In Vivo2008 Jan 01; 22
AB  - Canine anal sac gland carcinoma (ASGC) is a frequently described neoplasm that is highly aggressive and can frequently lead to metastatic spread. In this paper, we describe the successful treatment of an incompletely excised ASGC by using cisplatin selectively driven within the tumor cells by trains of biphasic pulses. The dog received two courses of electrochemotherapy 14 days apart. Neither systemic nor local toxicities were detected during the whole course of therapy. The dog is still in complete remission after 18 months. Electrochemotherapy is a safe and efficacious adjuvant therapy for ASGC and warrants further investigation in order to standardize its protocols. Copyright © 2008 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved