TY - JOUR T1 - Adjuvant Electrochemotherapy for Incompletely Excised Anal Sac Carcinoma in a Dog JF - In Vivo JO - In Vivo SP - 47 LP - 49 VL - 22 IS - 1 AU - ENRICO P. SPUGNINI AU - IVAN DOTSINSKY AU - NIKOLAY MUDROV AU - MASSIMILIANO BUFALINI AU - GIOVANNI GIANNINI AU - GENNARO CITRO AU - FLORINDA FEROCE AU - ALFONSO BALDI Y1 - 2008/01/01 UR - http://iv.iiarjournals.org/content/22/1/47.abstract N2 - Canine anal sac gland carcinoma (ASGC) is a frequently described neoplasm that is highly aggressive and can frequently lead to metastatic spread. In this paper, we describe the successful treatment of an incompletely excised ASGC by using cisplatin selectively driven within the tumor cells by trains of biphasic pulses. The dog received two courses of electrochemotherapy 14 days apart. Neither systemic nor local toxicities were detected during the whole course of therapy. The dog is still in complete remission after 18 months. Electrochemotherapy is a safe and efficacious adjuvant therapy for ASGC and warrants further investigation in order to standardize its protocols. Copyright © 2008 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved ER -