RT Journal Article
SR Electronic
T1 Effects of 4-<em>tert</em>-Octylphenol on the Incubation of Eggs in Japanese Brown Frogs (<em>Rana japonica</em>)
JF In Vivo
JO In Vivo
FD International Institute of Anticancer Research
SP 105
OP 108
VO 22
IS 1
A1 HIROAKI KAWAGUCHI
A1 YOSHIHISA UMEKITA
A1 MASAKAZU SOUDA
A1 HIROKI YOSHIDA
YR 2008
UL http://iv.iiarjournals.org/content/22/1/105.abstract
AB 4-tert-Octylphenol (OP), is an endocrine disruptor or surfactant widely used in herbicides. Its effects (0, 1 and 10 mg/l) on the incubation of eggs were examined using wild Japanese brown frogs (Rana japonica). In 10 mg/l OP, all the eggs were corrupted and no eggs developed. In 1 mg/l OP, 9.8% eggs developed and systemic edema, malformations such as crooked vertebrae and atrophy of the systemic muscles were observed in all the surviving tadpoles. These results suggested that OP use in paddy fields may affect the survival rate of wild frogs and induce malformation. Copyright © 2008 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved