PT  - JOURNAL ARTICLE
AU  - PARK, HAEKYUN
AU  - JANG, CHUL-HO
AU  - CHO, YONG BUM
AU  - CHOI, CHEOL-HEE
TI  - Antibacterial Effect of Tea-tree Oil on Methicillin-resistant <em>Staphylococcus aureus</em> Biofilm Formation of the Tympanostomy Tube: An <em>In Vitro</em> Study
DP  - 2007 Nov 01
TA  - In Vivo
PG  - 1027--1030
VI  - 21
IP  - 6
4099  - http://iv.iiarjournals.org/content/21/6/1027.short
4100  - http://iv.iiarjournals.org/content/21/6/1027.full
SO  - In Vivo2007 Nov 01; 21
AB  - The antibacterial effects of tea-tree oil against the formation of methicillin-resistant Staphylococcus aureus (MRSA) biofilm on the surface of the tympanostomy tubes was evaluated. Materials and Methods: Silicone tympanostomy tubes were pretreated with normal saline for 12 hours, the control group (n=4), with 100% tea-tree oil, experimental group A (n=3), or with 50% tea-tree oil, experimental group B (n=3). All the tubes were incubated in a MRSA solution for 2 days and then processed for evaluation using scanning electron microscopy. Results: The development of the biofilm mode of growth of MRSA was observed in the saline-treated control group. In contrast, only focal biofilms were present on the tube surface in experimental group A and considerable reduction of biofilm with destruction of the MRSA cells was shown in experimental group B. Conclusion: From these results, the antimicrobial effect of tea-tree oil against biofilm formation on tympanostomy tubes in vitro has been verified. Copyright © 2007 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved