PT  - JOURNAL ARTICLE
AU  - ZSUZSANNA HRACSKO
AU  - ZSOLT SAFAR
AU  - HAJNALKA ORVOS
AU  - ZOLTAN NOVAK
AU  - ATTILA PAL
AU  - ILONA S. VARGA
TI  - Evaluation of Oxidative Stress Markers after Vaginal Delivery or Caesarean Section
DP  - 2007 Jul 01
TA  - In Vivo
PG  - 703--706
VI  - 21
IP  - 4
4099  - http://iv.iiarjournals.org/content/21/4/703.short
4100  - http://iv.iiarjournals.org/content/21/4/703.full
SO  - In Vivo2007 Jul 01; 21
AB  - Background: The effects of vaginal delivery (VD) and of cesarean section (CS) on the markers of oxidative stress were investigated. Materials and Methods: Umbilical blood samples were analyzed from 74 full-term neonates, 46 born via VD, 28 via elective CS. The level of lipid peroxidation (LP), protein and DNA damage and the antioxidant status were compared. Results: Differences between CS and VD groups were generally non-significant for oxidative markers, except for the GSH concentrations (VD: 4.18 vs. CS: 2.77 μM/mg protein × 10-3; p<0.05). LP was significantly higher in the CS group (0.078 vs. 0.042 nM MDA/mg protein; p<0.05). The level of carbonyl proteins was high in the VD group and significantly lower in the elective CS group (9.5 vs. 8.1 mM/mg protein × 10-4; p<0.05). We found 0.78% more strand breaks in elective CS group than in VD group. Conclusion: CS does not have an advantage over VD with respect to oxidative stress. Copyright © 2007 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved