TY - JOUR T1 - Fluoroscopic-guided Intradiscal Oxygen-Ozone Injection Therapy for Thoracolumbar Intervertebral Disc Herniations in Dogs JF - In Vivo JO - In Vivo SP - 609 LP - 613 VL - 21 IS - 4 AU - HYUN-JUNG HAN AU - JOON-YOUNG KIM AU - HA-YOUNG JANG AU - BORA LEE AU - JUNG-HEE YOON AU - SANG-KEUN JANG AU - SEOK HWA CHOI AU - SOON-WUK JEONG Y1 - 2007/07/01 UR - http://iv.iiarjournals.org/content/21/4/609.abstract N2 - Background: To investigate the effect of oxygen-ozone (O2-O3) injection on thoracolumbar intervertebral disc herniation (IVDH) in dogs. Materials and Methods: Ten herniated discs of five dogs were treated with percutaneous injection of an O2-O3 gas mixture with O3 concentration of 32 μg/μl intradiscally (1.5-2 μl) under fluoroscopy guidance. Results: Five weeks after treatment, the mean size of herniated discs was measured by computed tomography and showed significant reduction of disc volumes in all animals (8.8%±3.82%). The degree of shrinkage was negatively linearly correlated with disc mineralization (correlation coefficient=-0.636) and statistically significant at p<0.05. All five dogs regained their gait function and none recurred. Conclusion: We conclude that intradiscal O2-O3 injection can decompress affected discs by disc shrinkage. Copyright © 2007 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved ER -