PT  - JOURNAL ARTICLE
AU  - HAN, HYUN-JUNG
AU  - KIM, JOON-YOUNG
AU  - JANG, HA-YOUNG
AU  - LEE, BORA
AU  - YOON, JUNG-HEE
AU  - JANG, SANG-KEUN
AU  - CHOI, SEOK HWA
AU  - JEONG, SOON-WUK
TI  - Fluoroscopic-guided Intradiscal Oxygen-Ozone Injection Therapy for Thoracolumbar Intervertebral Disc Herniations in Dogs
DP  - 2007 Jul 01
TA  - In Vivo
PG  - 609--613
VI  - 21
IP  - 4
4099  - http://iv.iiarjournals.org/content/21/4/609.short
4100  - http://iv.iiarjournals.org/content/21/4/609.full
SO  - In Vivo2007 Jul 01; 21
AB  - Background: To investigate the effect of oxygen-ozone (O2-O3) injection on thoracolumbar intervertebral disc herniation (IVDH) in dogs. Materials and Methods: Ten herniated discs of five dogs were treated with percutaneous injection of an O2-O3 gas mixture with O3 concentration of 32 μg/μl intradiscally (1.5-2 μl) under fluoroscopy guidance. Results: Five weeks after treatment, the mean size of herniated discs was measured by computed tomography and showed significant reduction of disc volumes in all animals (8.8%±3.82%). The degree of shrinkage was negatively linearly correlated with disc mineralization (correlation coefficient=-0.636) and statistically significant at p<0.05. All five dogs regained their gait function and none recurred. Conclusion: We conclude that intradiscal O2-O3 injection can decompress affected discs by disc shrinkage. Copyright © 2007 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved