PT - JOURNAL ARTICLE AU - MASUDA, HIROSHI AU - USHIYAMA, AKIRA AU - HIROTA, SHOGO AU - WAKE, KANAKO AU - WATANABE, SOICHI AU - YAMANAKA, YUKIO AU - TAKI, MASAO AU - OHKUBO, CHIYOJI TI - Effects of Subchronic Exposure to a 1439 MHz Electromagnetic Field on the Microcirculatory Parameters in Rat Brain DP - 2007 Jul 01 TA - In Vivo PG - 563--570 VI - 21 IP - 4 4099 - http://iv.iiarjournals.org/content/21/4/563.short 4100 - http://iv.iiarjournals.org/content/21/4/563.full SO - In Vivo2007 Jul 01; 21 AB - The aim of this study was to investigate whether repeated exposure to radio frequency electromagnetic field (RF-EMF) of 1439 MHz affects the cerebral microcirculation, including blood-brain barrier function, in a rat brain. Materials and Methods: The head of the rat was exposed for four weeks (60 min/day, 5 days/week) to RF-EMF at 2.4 W/kg of brain averaged specific absorption rate (BASAR). Three microcirculatory parameters: blood-brain barrier permeability, leukocyte behavior and plasma velocity were measured before and after RF-EMF exposure using a closed cranial window method. Results: No extravasation of intravenously injected dyes from pial venules was found at any BASAR level. No significant changes in the number of endothelial-adhering leukocytes after exposure were found. The plasma velocity remained constant within the physiological range through each exposure. Conclusion: These findings suggest that there were no effects on the cerebral microcirculation under the given RF-EMF exposure conditions. Copyright © 2007 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved