RT Journal Article
SR Electronic
T1 Effects of Acute Exposure to a 1439 MHz Electromagnetic Field on the Microcirculatory Parameters in Rat Brain
JF In Vivo
JO In Vivo
FD International Institute of Anticancer Research
SP 555
OP 562
VO 21
IS 4
A1 HIROSHI MASUDA
A1 AKIRA USHIYAMA
A1 SHOGO HIROTA
A1 KANAKO WAKE
A1 SOICHI WATANABE
A1 YUKIO YAMANAKA
A1 MASAO TAKI
A1 CHIYOJI OHKUBO
YR 2007
UL http://iv.iiarjournals.org/content/21/4/555.abstract
AB The aim of this study was to determine the potential of radio-frequency electromagnetic fields (RF-EMF) to affect cerebral microcirculation, including blood-brain barrier function, in rat brain. Materials and Methods: The head of the rat was exposed for 10 min to 1439 MHz RF-EMF having three intensity doses: 0.6, 2.4, 4.8 W/kg of brain averaged specific absorption rate (BASAR). Four microcirculatory parameters: blood-brain barrier permeability, leukocyte behavior, plasma velocity, and vessel diameter were measured before and after RF-EMF exposure using a closed cranial window method. Results: No extravasation of intravenously injected dyes from pial venules was found at any BASAR level. No significant changes in the number of endothelial-adhering leukocytes after exposure were found. The hemodynamics indicated that the plasma velocities and vessel diameters remained constant within the physiological range throughout each exposure. Conclusion: These findings suggest that there were no effects on the cerebral microcirculation under the given RF-EMF exposure conditions. Copyright © 2007 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved