<?xml version='1.0' encoding='UTF-8'?><xml><records><record><source-app name="HighWire" version="7.x">Drupal-HighWire</source-app><ref-type name="Journal Article">17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">BARÁTH, ZOLTÁN</style></author><author><style face="normal" font="default" size="100%">RADICS, RITA</style></author><author><style face="normal" font="default" size="100%">SPENGLER, GABRIELLA</style></author><author><style face="normal" font="default" size="100%">OCSOVSZKI, IMRE</style></author><author><style face="normal" font="default" size="100%">KAWASE, MASAMI</style></author><author><style face="normal" font="default" size="100%">MOTOHASHI, NOBORU</style></author><author><style face="normal" font="default" size="100%">SHIRATAKI, YOSHIAKI</style></author><author><style face="normal" font="default" size="100%">SHAH, ANAMIK</style></author><author><style face="normal" font="default" size="100%">MOLNÁR, JÓZSEF</style></author></authors><secondary-authors></secondary-authors></contributors><titles><title><style face="normal" font="default" size="100%">Multidrug Resistance Reversal by 3-Formylchromones in Human Colon Cancer and Human &lt;em&gt;mdr1&lt;/em&gt; Gene-transfected Mouse Lymphoma Cells</style></title><secondary-title><style face="normal" font="default" size="100%">In Vivo</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2006</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2006-09-01 00:00:00</style></date></pub-dates></dates><pages><style  face="normal" font="default" size="100%">645-649</style></pages><volume><style face="normal" font="default" size="100%">20</style></volume><issue><style face="normal" font="default" size="100%">5</style></issue><abstract><style  face="normal" font="default" size="100%">Several new 3-formylchromone derivatives proved to be modifiers of multidrug resistance in mouse lymphoma cells and in human Colo320 colon cancer cells. There is apparently a structure-activity relationship between the antiproliferative multidrug resistance-reversing effect and the chemical structure of the 3-formylchromones. The total polar surface areas and the ground state dipole moments of the molecules are presumed to play a key role in the multidrug resistance-reversing effect. The log P values can provide an adequate explanation for the selective cytotoxicity against cancer cells. Copyright © 2006 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved</style></abstract></record></records></xml>