TY - JOUR T1 - Radiation-induced Oral Mucositis in Brazilian Patients: Prevalence and Associated Factors JF - In Vivo JO - In Vivo SP - 605 LP - 609 DO - 10.21873/invivo.11517 VL - 33 IS - 2 AU - IGOR FIGUEIREDO PEREIRA AU - RAMON TARGINO FIRMINO AU - HENRIQUE CORTES MEIRA AU - BELMIRO CAVALCANTI DO EGITO VASCONCELOS AU - VLADIMIR REIMAR AUGUSTO DE SOUZA NORONHA AU - VAGNER RODRIGUES SANTOS Y1 - 2019/03/01 UR - http://iv.iiarjournals.org/content/33/2/605.abstract N2 - Aim: To determine the prevalence of radiation-induced oral mucositis (OM) and associated factors. Patients and Methods: A cross-sectional retrospective study was performed at a reference dental care center. The medical records of patients submitted to radiotherapy for the treatment of head and neck cancer were used to collect clinical and demographic variables. The data were submitted to descriptive analysis and multivariate Poisson regression with robust variance [p<0.05; 95% confidence intervaI (CI)]. Results: Four hundred and thirteen patients were analyzed. The mean age was 55±14 years. The prevalence of OM in the overall sample was 41.9% and was higher among males (78.2%). The following variables were significantly associated with the outcome: radiation dose [prevalence ratio (PR)= 1.04; 95% CI=1.02-1.06]; concomitant chemotherapy (PR=1.48, 95% CI=1.05-2.08); oral candidiasis (PR=1.97, 95% CI=1.44-2.68); and osteoradionecrosis (PR=1.51, 95% CI=1.10-2.06). Conclusion: Radiation-induced OM was associated with radiation dose, concomitant chemotherapy, oral candidiasis and osteoradionecrosis. The rate of OM underscores the importance of adequate oral care prior to treatment for head and neck cancer. ER -