RT Journal Article
SR Electronic
T1 Proteomics in Psoriasis: Recent Advances
JF In Vivo
JO In Vivo
FD International Institute of Anticancer Research
SP 1000
OP 1008
DO 10.21873/invivo.13533
VO 38
IS 3
A1 LEOTSAKOS, GEORGIOS
A1 KATAFIGIOTIS, IOANNIS
A1 LEOTSAKOS, IOANNIS
A1 KOUSTA, FIORI
A1 MOLYMPAKIS, ARISTEIDIS
A1 PERIMENI, AIKATERINI
A1 KOUTSILIERIS, MICHAEL
YR 2024
UL http://iv.iiarjournals.org/content/38/3/1000.abstract
AB Psoriasis continues to affect a large percentage of patients worldwide and strongly appears to be a systematic disease. Efforts are being made to understand its etiology, which have led to research extended to genomic analysis with a focus on the role of pro-inflammatory cytokines, which play a major role in the pathogenesis of the disease. Plasma proteomic analysis in various diseases has provided promising results for choosing the right treatment for psoriasis, suggesting that it could play a key role in the prevention, prognosis, and treatment of the disease by individualizing treatment choices based on the proteomic profile of each patient. In this review, we focus on existing data in the bibliography on proteomic analysis in psoriasis and relevant approaches to future targeted therapies.