RT Journal Article SR Electronic T1 Confined Low Grade Appendiceal Mucinous Neoplasm With Coexisting Distant Metastasis JF In Vivo JO In Vivo FD International Institute of Anticancer Research SP 295 OP 298 DO 10.21873/invivo.13438 VO 38 IS 1 A1 ARSHI, JUWAIRIYA A1 PETER, AMARJIT DAVID A1 LIANG, YUANXIN A1 HAO, YANSHENG YR 2024 UL http://iv.iiarjournals.org/content/38/1/295.abstract AB Background/Aim: Appendiceal mucinous neoplasms (AMNs) are tumors with dysplastic mucinous epithelium, a pushing growth pattern but no infiltrative invasion to the appendiceal wall. Some AMNs are associated with pseudomyxoma peritonei, characterized by intraperitoneal mucinous involvement. Recent studies have demonstrated that LAMNs confined to the appendix have low or no risk for disease recurrence, progression, and peritoneal involvement during follow up. Case Report: Here, we present two extremely rare cases with confined low grade appendiceal mucinous neoplasm (pTis and pT3) and simultaneous extraperitoneal subcutaneous or ovary involvement at the time of diagnosis. Conclusion: Our cases demonstrate that although the primary tumor is limited to the appendix, coexisting distant metastasis may occur on very rare occasions.