RT Journal Article
SR Electronic
T1 Efficacy of Percutaneous Direct Puncture Biopsy of Malignant Lung Tumors Contacting to the Pleura
JF In Vivo
JO In Vivo
FD International Institute of Anticancer Research
SP 2237
OP 2243
DO 10.21873/invivo.13325
VO 37
IS 5
A1 HIROSHI KODAMA
A1 HARUYUKI TAKAKI
A1 JUNICHI TANIGUCHI
A1 ATSUSHI OGASAWARA
A1 YASUKAZU KAKO
A1 KAORU KOBAYASHI
A1 KOICHIRO YAMAKADO
YR 2023
UL http://iv.iiarjournals.org/content/37/5/2237.abstract
AB Background/Aim: This is a retrospective evaluation of whether percutaneous direct puncture biopsy of lung lesions contacting to the pleura is justified. Patients and Methods: Between August 2016 and July 2021, 163 consecutive patients (100 males, 63 females with a median age of 73 years) who had malignant lung tumors measuring 0.6-12.4 cm (median, 2.9 cm) that contacted to the pleura and underwent percutaneous lung biopsy under computed tomography fluoroscopic guidance using an 18-gauge end-cut needle were examined. The trajectory was direct puncture in 80 patients (49.1%, 80/163), and trans-lung in 83 patients (50.9%, 83/163). Diagnostic yield and major adverse event rates of direct and trans-lung puncture biopsies were compared. Results: No difference was found in diagnostic yield between direct puncture and trans-lung biopsies (93.8% vs. 98.8%, p=0.11). Major adverse events were major pneumothorax (n=13/163, 8.0%), pleural dissemination (n=18/163, 11.0%), and hemothorax requiring arterial embolization (n=1/163, 1.0%). Direct puncture caused major pneumothorax significantly less than trans-lung puncture did (0%, 0/80 vs. 15.7%, 13/83, p<0.001). No significant difference was found between the two biopsy methods regarding the incidence of pleural dissemination (11.0%, 11/80 vs. 8.4%, 7/83, p=0.32). Conclusion: Direct puncture biopsy of malignant lung tumors contacting to the pleura is justified.