PT  - JOURNAL ARTICLE
AU  - HIROSHI KODAMA
AU  - HARUYUKI TAKAKI
AU  - JUNICHI TANIGUCHI
AU  - ATSUSHI OGASAWARA
AU  - YASUKAZU KAKO
AU  - KAORU KOBAYASHI
AU  - KOICHIRO YAMAKADO
TI  - Efficacy of Percutaneous Direct Puncture Biopsy of Malignant Lung Tumors Contacting to the Pleura
AID  - 10.21873/invivo.13325
DP  - 2023 Sep 01
TA  - In Vivo
PG  - 2237--2243
VI  - 37
IP  - 5
4099  - http://iv.iiarjournals.org/content/37/5/2237.short
4100  - http://iv.iiarjournals.org/content/37/5/2237.full
SO  - In Vivo2023 Sep 01; 37
AB  - Background/Aim: This is a retrospective evaluation of whether percutaneous direct puncture biopsy of lung lesions contacting to the pleura is justified. Patients and Methods: Between August 2016 and July 2021, 163 consecutive patients (100 males, 63 females with a median age of 73 years) who had malignant lung tumors measuring 0.6-12.4 cm (median, 2.9 cm) that contacted to the pleura and underwent percutaneous lung biopsy under computed tomography fluoroscopic guidance using an 18-gauge end-cut needle were examined. The trajectory was direct puncture in 80 patients (49.1%, 80/163), and trans-lung in 83 patients (50.9%, 83/163). Diagnostic yield and major adverse event rates of direct and trans-lung puncture biopsies were compared. Results: No difference was found in diagnostic yield between direct puncture and trans-lung biopsies (93.8% vs. 98.8%, p=0.11). Major adverse events were major pneumothorax (n=13/163, 8.0%), pleural dissemination (n=18/163, 11.0%), and hemothorax requiring arterial embolization (n=1/163, 1.0%). Direct puncture caused major pneumothorax significantly less than trans-lung puncture did (0%, 0/80 vs. 15.7%, 13/83, p<0.001). No significant difference was found between the two biopsy methods regarding the incidence of pleural dissemination (11.0%, 11/80 vs. 8.4%, 7/83, p=0.32). Conclusion: Direct puncture biopsy of malignant lung tumors contacting to the pleura is justified.