TY - JOUR T1 - Induction of Apoptosis in Human Promyelocytic Leukemia HL-60 Cells by <em>Ampelopsis cantoniensis</em> Crude Extract JF - In Vivo JO - In Vivo SP - 457 LP - 462 VL - 18 IS - 4 AU - TZU-WEI TAN AU - HUEI-YANN TSAI AU - YUH-FUNG CHEN AU - JING-GUNG CHUNG Y1 - 2004/07/01 UR - http://iv.iiarjournals.org/content/18/4/457.abstract N2 - The crude extract of Ampelopsis cantoniensis induced apoptosis in human promyelocytic leukemia HL-60 cells and this induction was investigated by flow cytometric analysis, DNA gel electrophoresis and poly (ADP-ribose) fluorescence staining. The results demonstrated that this extract induced dose-dependent cytotoxicity and apoptosis. The level of active caspase-3 was increased after treatment with the crude extract for 24 hours. ER -