RT Journal Article
SR Electronic
T1 Peak of Standardized Uptake Value in Oral Cancer Predicts Survival Adjusting for Pathological Stage
JF In Vivo
JO In Vivo
FD International Institute of Anticancer Research
SP 1193
OP 1198
DO 10.21873/invivo.11363
VO 32
IS 5
A1 SUZUKI, HIDENORI
A1 TAMAKI, TSUNEO
A1 NISHIO, MASAMI
A1 BEPPU, SHINTARO
A1 MUKOYAMA, NOBUAKI
A1 HANAI, NOBUHIRO
A1 NISHIKAWA, DAISUKE
A1 KOIDE, YUSUKE
A1 HASEGAWA, YASUHISA
YR 2018
UL http://iv.iiarjournals.org/content/32/5/1193.abstract
AB Background/Aim: To predict survival outcomes of different patients with the same stage of disease is difficult. The possible correlation between 18F-fluorodeoxyglucose (18F-FDG) uptake parameters and survival outcomes was investigated in oral squamous cell carcinoma patients by multivariate analysis adjusted for the pathological stage according to the 8th edition of the tumor-node-metastasis (TNM) classification of the Union for International Cancer Contro. Patients and Methods: 18F-FDG-uptake parameters of 28 patients were assessed by positron emission tomography with computed tomography (PET/CT). Results: A peak of standardized uptake value of primary tumor (p-SUVpeak) of ≥14.1 was significantly correlated with shorter overall survival by univariate and multivariate analyses adjusted for the pathological TNM stage. A p-SUVpeak of ≥14.1 was significantly associated with shorter local recurrence-free survival and disease-free survival. Conclusion: A higher p-SUVpeak on pretreatment 18F-FDG-PET/CT is a prognostic parameter of identifying lower survival outcomes.