PT  - JOURNAL ARTICLE
AU  - SUZUKI, HIDENORI
AU  - TAMAKI, TSUNEO
AU  - NISHIO, MASAMI
AU  - BEPPU, SHINTARO
AU  - MUKOYAMA, NOBUAKI
AU  - HANAI, NOBUHIRO
AU  - NISHIKAWA, DAISUKE
AU  - KOIDE, YUSUKE
AU  - HASEGAWA, YASUHISA
TI  - Peak of Standardized Uptake Value in Oral Cancer Predicts Survival Adjusting for Pathological Stage
AID  - 10.21873/invivo.11363
DP  - 2018 Sep 01
TA  - In Vivo
PG  - 1193--1198
VI  - 32
IP  - 5
4099  - http://iv.iiarjournals.org/content/32/5/1193.short
4100  - http://iv.iiarjournals.org/content/32/5/1193.full
SO  - In Vivo2018 Sep 01; 32
AB  - Background/Aim: To predict survival outcomes of different patients with the same stage of disease is difficult. The possible correlation between 18F-fluorodeoxyglucose (18F-FDG) uptake parameters and survival outcomes was investigated in oral squamous cell carcinoma patients by multivariate analysis adjusted for the pathological stage according to the 8th edition of the tumor-node-metastasis (TNM) classification of the Union for International Cancer Contro. Patients and Methods: 18F-FDG-uptake parameters of 28 patients were assessed by positron emission tomography with computed tomography (PET/CT). Results: A peak of standardized uptake value of primary tumor (p-SUVpeak) of ≥14.1 was significantly correlated with shorter overall survival by univariate and multivariate analyses adjusted for the pathological TNM stage. A p-SUVpeak of ≥14.1 was significantly associated with shorter local recurrence-free survival and disease-free survival. Conclusion: A higher p-SUVpeak on pretreatment 18F-FDG-PET/CT is a prognostic parameter of identifying lower survival outcomes.