RT Journal Article SR Electronic T1 Advanced Gastric Cancer With Intramural Abscess: A Case Report of a Rare Clinicopathological Condition JF In Vivo JO In Vivo FD International Institute of Anticancer Research SP 1998 OP 2001 DO 10.21873/invivo.12925 VO 36 IS 4 A1 OGINO, SHINPEI A1 KOSUGA, TOSHIYUKI A1 SHODA, KATSUTOSHI A1 KUBOTA, TAKESHI A1 OKAMOTO, KAZUMA A1 OTSUJI, EIGO YR 2022 UL http://iv.iiarjournals.org/content/36/4/1998.abstract AB Background: Gastric wall abscess (GWA) itself is a rare clinicopathological condition, and there has been no report of primary gastric cancer complicated by GWA. Herein, we present a case of advanced gastric cancer with intramural abscess, which was successfully treated with curative gastrectomy. Case Report: A 77-year-old woman was admitted to the hospital for dull epigastric pain with inflammatory findings and diagnosed with advanced gastric cancer (cT4aN1M0 Stage III) with intramural abscess. Since an endoscopic ultrasonography-guided abscess drainage was not effective, after conservative therapy with antibiotics, she underwent distal gastrectomy with D2 lymphadenectomy and fortunately the tumor with abscess was safely and curatively removed without perforation. Microscopically, the 82×65 mm tumor invaded the subserosa and contained tubular adenocarcinoma with neuroendocrine cell carcinoma (pT3N0M0 Stage IIB), and the abscess formed from the ulcerative lesion of the cancer extended to the subserosa. The postoperative clinical course was uneventful, and she remained disease-free during the 22 months follow-up. Conclusion: Given the nature of the disease and the difficulty in endoscopic treatment, gastrectomy should be performed immediately for advanced gastric cancer with GWA to ensure control of both gastric cancer and infection.