TY - JOUR T1 - Pre-treatment CRP and Albumin Determines Prognosis for Unresectable Advanced Oesophageal Cancer JF - In Vivo JO - In Vivo SP - 1930 LP - 1936 DO - 10.21873/invivo.12914 VL - 36 IS - 4 AU - MAKOTO SOHDA AU - MAKOTO SAKAI AU - ARISA YAMAGUCHI AU - TAKAYOSHI WATANABE AU - NOBUHIRO NAKAZAWA AU - YASUNARI UBUKATA AU - KENGO KURIYAM AU - AKIHIKO SANO AU - TAKEHIKO YOKOBORI AU - HIROOMI OGAWA AU - KEN SHIRABE AU - HIROSHI SAEKI Y1 - 2022/07/01 UR - http://iv.iiarjournals.org/content/36/4/1930.abstract N2 - Background/Aim: Nutritional disorders due to cancer-related weight loss, such as cancer-impaired food passage, are prominent in many cases of advanced oesophageal cancer. Here, we investigated the nutritional factors that most affect the therapeutic effect and prognosis of unresectable oesophageal cancer. Patients and Methods: One hundred four patients diagnosed with cT4b oesophageal squamous cell carcinoma were included in this study. The values of C-reactive protein/albumin ratio, Glasgow Prognostic Score, prognostic nutritional index, neutrophil/lymphocyte ratio and platelet/lymphocyte ratio were calculated from the pre-treatment blood sampling results of the patients who received chemoradiotherapy, and the therapeutic effect and prognosis were analysed. Results: High- C-reactive protein/albumin group and Glasgow Prognostic Score 1 or 2 group correlated with a significantly worse prognosis compared with the low- C-reactive protein/albumin group and Glasgow Prognostic Score 0 group regarding both disease-specific survival and overall survival. Conclusion: Evaluation of pre-treatment CRP and albumin levels in locally advanced oesophageal cancer leads to useful prognostic prediction. ER -