RT Journal Article SR Electronic T1 Background Parenchymal Enhancement in Contrast-enhanced Spectral Mammography: A Retrospective Analysis and a Pictorial Review of Clinical Cases JF In Vivo JO In Vivo FD International Institute of Anticancer Research SP 853 OP 858 DO 10.21873/invivo.12773 VO 36 IS 2 A1 ROSARIA MEUCCI A1 CHIARA ADRIANA PISTOLESE A1 TOMMASO PERRETTA A1 GIANLUCA VANNI A1 EMANUELA BENINATI A1 FEDERICA DI TOSTO A1 MARIA LINA SERIO A1 AURELIA CALIANDRO A1 MARCO MATERAZZO A1 MARCO PELLICCIARO A1 ORESTE CLAUDIO BUONOMO YR 2022 UL http://iv.iiarjournals.org/content/36/2/853.abstract AB Background/Aim: Despite the popularity of contrast enhanced spectral mammography (CESM), univocal classification of the background parenchymal enhancement (BPE), a bilateral enhancement of the normal breast parenchyma after contrast administration, is lacking. The present study aimed to evaluate the application of BPE Breast Imaging Reporting and Data System Magnetic Resonance (BI-RADS-MR) score for the CESM BPE. Moreover, a pictorial review of four different cases with CESM is provided. Patients and Methods: A single-center, retrospective study from a prospectively maintained database of all women undergoing digital mammography (DM) and CESM in our institution between 2016 and 2019. DM and CESM were classified by two experienced radiologists. Results: No statistically significant difference between DM breast density and BPE CESM classification was found. Agreement between readers ranged from substantial to almost perfect. Conclusion: BIRADS-RM score for the CESM BPE represents a handy option for radiologists with high inter-reader and DM agreement.