TY - JOUR T1 - The Association of the Lymphocyte-to-C-Reactive-Protein Ratio With Gastric Cancer Patients Who Receive Curative Treatment JF - In Vivo JO - In Vivo SP - 482 LP - 489 DO - 10.21873/invivo.12728 VL - 36 IS - 1 AU - TORU AOYAMA AU - MASATO NAKAZANO AU - SHINSUKE NAGASAWA AU - KENTARO HARA AU - KEISUKE KOMORI AU - HIROSHI TAMAGAWA AU - YUKIO MAEZAWA AU - KENKI SEGAMI AU - KAZUKI KANO AU - TAKASHI OGATA AU - NORIO YUKAWA AU - YASUSHI RINO AU - TAKASHI OSHIMA Y1 - 2022/01/01 UR - http://iv.iiarjournals.org/content/36/1/482.abstract N2 - Background/Aim: We investigated the association of the preoperative lymphocyte-to-C-reactive-protein ratio (LCR) with gastric cancer survival and recurrence after curative treatment. Patients and Methods: This study included 480 patients who underwent curative surgery followed by adjuvant treatment for gastric cancer between 2013 and 2017. The prognostic factors for overall survival (OS) and recurrence-free survival (RFS) were identified. Results: A LCR of 7,000 was regarded as the optimal critical point of classification, considering the 1-, 3- and 5-year survival rates. The OS rates at 3 and 5 years after surgery were 84.4% and 73.9% in the low-LCR group, respectively, and 92.4% and 87.0% in the high-LCR group, respectively, and were statistically significantly different. The RFS rates at 3 and 5 years after surgery were 78.8% and 68.7% in the low-LCR group, respectively, and 89.3% and 86.6% in the high-LCR group, respectively, with a statistically significant difference. A multivariate analysis showed that the LCR was a significant independent prognostic factor for both OS and RFS. Conclusion: The LCR was a significant prognostic factor for survival in patients who underwent curative treatment for gastric cancer. ER -