PT - JOURNAL ARTICLE AU - MICHELANGELO RUSSILLO AU - GIANLUIGI FERRETTI AU - ANTONELLO VIDIRI AU - SIMONA GASPARRO AU - FRANCESCO COGNETTI AU - DOMENICA PELLEGRINI AU - ALESSANDRA FABI TI - Impressive Long-term Response with Pertuzumab and Trastuzumab in HER2-positive Breast Cancer with Brain Metastasis AID - 10.21873/invivo.11317 DP - 2018 Jul 01 TA - In Vivo PG - 839--842 VI - 32 IP - 4 4099 - http://iv.iiarjournals.org/content/32/4/839.short 4100 - http://iv.iiarjournals.org/content/32/4/839.full SO - In Vivo2018 Jul 01; 32 AB - This is a case report of a 40-year-old woman who, after conservative breast cancer treatment, developed a HER2 positive solitary brain metastasis in the left temporal lobe, without extracranial disease. She underwent surgery resection followed by stereotactic radiotherapy and, because of early brain progression, she was submitted to the first line therapy with pertuzumab, trastuzumab and weekly paclitaxel. After six months of treatment, a brain magnetic resonance imaging revealed a complete disappearance of brain recurrence, which persisted for more than 24 months.