TY - JOUR T1 - Efficacy of Intravenous Use of Lidocaine in Postoperative Pain Management After Laparoscopic Colorectal Surgery: A Meta-analysis and Meta-regression of RCTs JF - In Vivo JO - In Vivo SP - 3413 LP - 3421 DO - 10.21873/invivo.12641 VL - 35 IS - 6 AU - CHAMAIDI SARAKATSIANOU AU - KONSTANTINOS PERIVOLIOTIS AU - GEORGE TZOVARAS AU - ATHINA A. SAMARA AU - IOANNIS BALOYIANNIS Y1 - 2021/11/01 UR - http://iv.iiarjournals.org/content/35/6/3413.abstract N2 - Background/Aim: Current literature reports regarding the effect of lidocaine in laparoscopic colectomies are still inconclusive. The purpose of this study was to review the current literature and estimate the overall effect of intravenous lidocaine administration in postoperative recovery of patients submitted to laparoscopic colectomies. Materials and Methods: This study was completed based on the PRISMA guidelines and the Cochrane Handbook for Systematic Reviews of Interventions. A systematic screening using scholar databases was performed (Medline, Scopus, Web of Science, CENTRAL). Results: In total, 8 studies and 407 patients were included in this meta-analysis. Introduction of intravenous lidocaine in the perioperative analgesia scheme did not improve hospitalization duration (p=0.23), morphine consumption (p=0.96), perioperative bowel function (first flatus p=0.40, first bowel opened p=0.13, first diet p=0.16), or the overall complication rates (p=0.42). Overall, high heterogeneity levels were identified. Conclusion: Current evidence indicates that lidocaine does not improve rehabilitation after laparoscopic colectomies. ER -