TY - JOUR T1 - Distal Pancreatectomy With Celiac Axis Resection for Locally Advanced Pancreatic Body Cancer – A Case Report and Literature Review JF - In Vivo JO - In Vivo SP - 3627 LP - 3631 DO - 10.21873/invivo.12669 VL - 35 IS - 6 AU - NICOLAE BACALBASA AU - IRINA BALESCU AU - MIHAI DIMITRIU AU - CRISTIAN BALALAU AU - FLORENTINA FURTUNESCU AU - FLORENTINA GHERGHICEANU AU - DANIEL RADAVOI AU - CAMELIA DIACONU AU - OVIDIU STIRU AU - CORNEL SAVU AU - VLADISLAV BRASOVEANU AU - CLAUDIA STOICA AU - IOAN CORDOS Y1 - 2021/11/01 UR - http://iv.iiarjournals.org/content/35/6/3627.abstract N2 - Background: Locally advanced pancreatic cancer invading the surrounding vascular structures has long been considered as unresectable and, therefore, patients were usually submitted to palliative chemotherapy. Case Report: We present the case of a 44-year-old male investigated for weight loss and abdominal pain and diagnosed with a locally advanced pancreatic tumor invading the celiac axis. An endoscopic ultrasound was performed and a biopsy was retrieved demonstrating the presence of a moderately differentiated pancreatic adenocarcinoma. After discussing with the patient the risks and the benefits of performing an extended surgical procedure, the patient consented to distal pancreatectomy en bloc with celiac axis resection. Postoperatively, the patient was submitted to low-molecular-weight heparin therapy for 3 weeks followed by oral anticoagulant for 2 months. Histopathological studies confirmed the presence of a moderately differentiated pancreatic adenocarcinoma invading the celiac axis and described negative resection margins. Conclusion: Although celiac axis invasion has been considered for a long period of time as a sign of unresectable disease due to the high rates of perioperative complications, it seems that in selected cases, surgery can be safely performed with curative intent, especially if negative resection margins are achieved. ER -