PT  - JOURNAL ARTICLE
AU  - SUGURU ODAJIMA
AU  - KAZU UEDA
AU  - SATOSHI HOSOYA
AU  - KEISUKE TOMITA
AU  - SAYAKO KATO
AU  - YUICHI SHOBURU
AU  - AYAKO KAWABATA
AU  - YASUSHI IIDA
AU  - NOZOMU YANAIHARA
AU  - AIKOU OKAMOTO
TI  - Clinical Availability of Tumour Biopsy Using Diagnostic Laparoscopy for Advanced Ovarian Cancer
AID  - 10.21873/invivo.12629
DP  - 2021 Nov 01
TA  - In Vivo
PG  - 3325--3331
VI  - 35
IP  - 6
4099  - http://iv.iiarjournals.org/content/35/6/3325.short
4100  - http://iv.iiarjournals.org/content/35/6/3325.full
SO  - In Vivo2021 Nov 01; 35
AB  - Background/Aim: Tumour biopsy using laparoscopy before neoadjuvant chemotherapy for advanced ovarian cancer has been widely accepted. However, there are few reports about its operative outcome compared to biopsy with laparotomy. We investigated the advantage of laparoscopic biopsy for advanced ovarian cancer. Patients and Methods: We included 23 patients who underwent laparoscopy and 27 who underwent exploratory laparotomy before neoadjuvant chemotherapy between January 2012 and August 2020. We reviewed their medical records and evaluated their operative outcomes. Results: Blood loss was significantly lower in the laparoscopy group (5 ml vs. 320 ml, p<0.05). The period until the initiation of neoadjuvant chemotherapy was significantly shorter in the laparoscopy group (12 days vs. 16 days, p<0.05). Overall survival did not differ significantly between the two groups (25.4 months vs. 24.7 months, p=0.53). Conclusion: Laparoscopic tumour biopsy is useful and safe for histological diagnosis, thereby allowing for early introduction to neoadjuvant chemotherapy.